Spectroscopic studies of naproxen and tryptophan immobilized in polyvinyl alcohol
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Keywords

PVA
polyvinyl alcohol
polymer
naproxen
tryptophan
spectroscopic
fluorescence
absorption

How to Cite

Sabara, D. M., Dunne, J. S., Pedro, A. Q., Trifunović, J., Balogun5. I., Kotlicic, O., Serrano, A., & Kertész, I. (2011). Spectroscopic studies of naproxen and tryptophan immobilized in polyvinyl alcohol. Biotechnology and Food Science, 75(1), 39-49. https://doi.org/10.34658/bfs.2011.75.1.39-49

Abstract

Hydrogels are cross-linked hydrophilic polymer networks that find application in biomedical and pharmaceutical industries due to their unique properties. Polyvinyl alcohol is a synthetic polymer, potential biomaterial blended with various materials and compounds, that can provide new options for drug delivery systems. Determination of photochemical properties of naproxen and tryptophan immobilized in polyvinyl alcohol and two other media: water and cyclohexane was performed using UV-Vis absorption and fluorescence methods. The influences of the media used on the spectral properties of naproxen and tryptophan have been shown.

https://doi.org/10.34658/bfs.2011.75.1.39-49
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References

Lakowicz JR. Topics in Fluorescence Spectroscopy. Plenum Press, New York, USA, 1992.

Pan Y-s, Xiong D-s, Ma R-y. Preparation and swelling behavior of polyvinyl alcohol physiological saline gel. J. Cent. South Univ. T. 2006, 13:27-31.

Yang D, Li Y, Nie J. Preparation of gelatin/PVA nanofibers and their potential application in controlled release of drugs. Carbohydr. Polym. 2007, 69:538-543.

Chatterjee J, Haik Y, Chen C. A biocompatible magnetic film: synthesis and characterization. BioMagn. Res. Technol. 2004, 2:2.

Mc Gann MJ, Higginbotham CL, Geever LM, Nugent MJD. The synthesis of novel pH-sensitive poly(vinyl alcohol) composite hydrogels using a freeze/thaw process for biomedical applications. Int. J. Pharm. 2009, 372:154-161.

Basak P, Adhikari B. Poly (vinyl alcohol) hydrogels for pH dependent colon targeted drug delivery. J. Mater. Sci.: Mater.Med. 2009, 20:137-146.

Chiellini E, Cinelli P; Fernes, Elizabeth G; Kenawy El-Refaie S; Lazzeri A. Gelatin-based blends and composites, morphological and thermal mechanical characterization. Biomacromolecules 2001, 2:806-811.

Nechifor C-D, Ciobanu CL, Dorohoi D-O, Ciobanu C. Polymeric films properties of Poly(vinyl alcohol) and Poly(hydroxy urethane) in different concentrations. UPB Sci. Bull., Series A 2009, 71.

Liu Y, Vrana NE, Cahill PA, McGuinness GB. Physically crosslinked composite hydrogels of PVA with natural macromolecules: Structure, mechanical properties, and endothelial cell compatibility. J. Biomed. Mater. Res., Part B: Appl. Biomater. 2009, 90B:492-502.

Mendieta-Taboada O., Sobral PJdA, Carvalho RA, Habitante AMBQ. Thermomechanical properties of biodegradable films based on blends of gelatin and poly(vinyl alcohol). Food Hydrocolloids 2008, 22:1485-1492.

Gholap SG, Jog JP, Badiger MV. Synthesis and characterization of hydrophobically modified poly(vinyl alcohol) hydrogel membrane. Polymer 2004, 45:5863-5873.

Amer M, Bead VR, Bathon J, Blumenthal RS, Edwards D.N. Use of Nonsteroidal Anti-Inflammatory Drugs in Patients With Cardiovascular Disease: A Cautionary Tale. Cardiol. Rev. 2010, 18:204-212. 13. Lapresta-Fernández A, Cywinski P, Moro A, Mohr G. Fluorescent polyacrylamide nanoparticles for naproxen recognition. Anal. Bioanal. Chem. 2009,395:1821-1830.

Matsumoto S, Nishimoto E, Soejima H, Yamashita S. The Quenching-Resolved Fluorescence Spectrum and Its Application to Studies of the Folding/Unfolding of Trypsin Inhibitor from Seeds of the Bitter Gourd. Biosci. Biotechnol. Biochem. 2010, 74:1396-1402.

Resch-Genger U., Standardization and quality assurance in fluorescence measurements I, Springer, 2008.

Axtmann RC. Principles of photochemistry. by J. A. Barltrop and J. D. Coyle, John Wiley and Sons, AIChE J., 1982, 28:869-869.

Doretti L, Ferrara D, Gattolin P, Lora S, Schiavon F, et al. PEG-modified glucose oxidase immobilized on a PVA cryogel membrane for amperometric biosensor applications. Talanta 1998, 45:891-898.

Doretti L, Ferrara D, Gattolin P, Lora S. Amperometric biosensor with physically immobilized glucose oxidase on a PVA cryogel membrane. Talanta 1997, 44:859-866.

Maruyama K, Akahoshi H, Kobayashi M, Tanizaki Y. Assignment of conjugate double bond systems produced in heated PVA film by absorption and excitation spectra. Bull. Chem. Soc. Jap. 1985, 58:2923-2928.

Smirnov LV, Platonova NV, Kulikova NP. Electronic absorption spectra of polyvinyl alcohol. J. Appl. Spectrosc. 1968, 8:197-202.

Moore DE, Chappuis PP. A Comparative study of the photochemistry of the non-steroidal anti-inflammatory drugs, Naproxen, Benoxaprofen and Indomethacin. Photochem. Photobiol. 1988, 47:173-180.

Neely RK, Tamulaitis G, Chen K, Kubala M., Siksnys V, et al. Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes. Nucleic Acids Res. 2009, 37:6859-6870.

Millar DP. Time-resolved fluorescence spectroscopy. Curr. Opin. Struct. Biol. 1996, 6:637-642.

Lakowicz JR, Balter A. Differential-wavelength deconvolution of time-resolved fluorescence intensities: A new method for the analysis of excited-state processes. Biophys.Chem. 1982, 16:223-240.

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